们研究了全基因组染色质相

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附加文件：图4）。猪骨骼肌全基因组染色质相互作用模式我互作用模式，以揭示327介导的染色质相互作用在转录水平上的影响。我们比较了活性启动子（）和增强子（）（有或没有）调控的基因的表达模式（图2），发现，正如预期的那样，有相互作用的基因比没有相应相互作用的基因表现出更高的表达水平。相互作用，并且具有相互作用的基因也比没有相应相互作用的基因具有更高的表达水平。相比之下，具有相互作用的基因的表达水平显着高于具有相互作用的基因（图2和附加文件）：图5），这可以通过（近端元件）可能

比（远端元件）施加更强的影响来解释。图2图2染色质相互作用和基因表达的综合分C级执行名单析。受或不受活性启动子()和增强子()调控的基因。型，无和基因；型，带有但不带有的基因；型，有但没有的基因；型，分别具有和的基因。单尾在中表达四种类型的基因：型（638）、型（38）、型（263）和型（834）使用值从左到右进行测试：42×3、×38和69×6。循环交互类型百分比的圆环图（饼图）。，两个锚点都覆盖有增强剂的循环；，两个锚点都覆

盖有活性启动子的环；，一个锚点覆盖有活性启动子，另一个锚点覆盖有增强子的环；无，只有一个锚点覆盖有增强剂的循环；无，只有一个锚点覆盖有活性启动子的环；不清楚，没有锚点的环覆盖有活性启动子和增强子。根据中增强子的数量分类的基因表达。进行平均基因表达水平的线性回归（值<22×6，检验）。3交互和中增强子的数量不同。和中与不同数量的增强子的相互作用全尺寸图像此外，为了检查327环介导的整体染色质特征，环连接的顺式调节元件的类型用于对染色质相互作用类型进行分类。染色质相互作用环在活性顺式调节区域中

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